Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 4/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 6/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363845 | 0.95 | TLR8 (0.45) | NAAANQO2PRKCITLR8CISD1 | |
| SCHEMBL27139926 | 0.88 | IDO1 (0.50) | NQO2PRKCICISD1ACHEPDE10A | |
| SCHEMBL7173917 | 0.83 | NAAA (0.56) | NAAATRPV1IDO1HCAR3KDM4E | |
| SCHEMBL2901815 | 0.81 | PLK1 (0.46) | NAAA | |
| SCHEMBL9650900 | 0.81 | ABL1 (0.50) | NAAATRPV1IDO1HCAR3ALDH1A1 | |
| SCHEMBL27534388 | 0.80 | IDO1 (0.47) | PRKCIACHEPDE10AIDO1KDM4E | |
| SCHEMBL29069494 | 0.80 | TRPA1 (0.48) | NAAATRPV1MEN1MAPTKMT2A | |
| SCHEMBL45593 | 0.79 | NAAA (0.50) | NAAATLR8IDO1KDM4EMEN1 | |
| SCHEMBL5707666 | 0.79 | CA1 (0.41) | PRKCIACHEPDE10AIDO1KDM4E | |
| SCHEMBL9645556 | 0.79 | TLR7 (0.41) | NQO2TLR8HCAR3KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285109-B1 | PROCESS FOR THE PREPARATION OF 2-AMINO-4-ACYLAMINO-PHENYL ETHER | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | disclosed |
| EP-0285109-A1 | Process for the preparation of 2-amino-4-acylamino-phenyl ether | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | disclosed |