SCHEMBL9645581

SCHEMBL9645581

Cc1ccc(Nc2cc(N)ccc2O)cc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 2/20 0.58
TSHR P16473 1/20 0.58
PDE10A Q9Y233 1/20 0.48
KDR P35968 6/20 0.42
EGFR P00533 5/20 0.42
FLT1 P17948 1/20 0.42
FLT4 P35916 1/20 0.42
BRAF P15056 2/20 0.41
RAF1 P04049 1/20 0.41
RAPGEF4 Q8WZA2 1/20 0.41
ALDH1A1 P00352 5/20 0.40
RECQL P46063 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
CYP3A4 P08684 2/20 0.40
MEN1 O00255 2/20 0.40
GAA P10253 2/20 0.40
KMT2A Q03164 2/20 0.40
THRB P10828 1/20 0.40
ALOX15 P16050 1/20 0.40
HIF1A Q16665 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17526998 0.89 CASP1 (0.50) CASP1TSHRPDE10ARAPGEF4ALDH1A1
SCHEMBL17506795 0.79 MAPT (0.43) CASP1TSHRPDE10AKDRRAPGEF4
SCHEMBL17508259 0.78 TDP1 (0.56) CASP1TSHRPDE10AKDREGFR
SCHEMBL17498347 0.78 CA1 (0.50) CASP1TSHRPDE10AKDRRAPGEF4
SCHEMBL17506827 0.77 TDP1 (0.55) PDE10ABRAFRAF1RAPGEF4ALDH1A1
SCHEMBL17498289 0.77 PDE10A (0.53) CASP1TSHRPDE10AKDRALDH1A1
SCHEMBL11511599 0.76 TSHR (0.47) CASP1TSHRPDE10ARAPGEF4ALDH1A1
SCHEMBL17526997 0.75 CYP3A4 (0.54) CASP1TSHRKDREGFRFLT1
SCHEMBL11648797 0.75 PDE10A (0.56) CASP1TSHRPDE10ARAPGEF4ALDH1A1
SCHEMBL29670126 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5085978-A METHOD FOR PROCESSING LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1992-02-04 US claimed