Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SNCA | P37840 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494943 | 0.88 | MAPT (0.46) | TSHRCASP1PDE10AMAPTKDM4E | |
| SCHEMBL11556252 | 0.81 | GAA (0.50) | TSHRMAPTKDM4EALOX15HPGD | |
| SCHEMBL11785715 | 0.80 | PKM (0.43) | TSHRCASP1PDE10AMAPTKDM4E | |
| SCHEMBL4011162 | 0.79 | FCGR3B (0.39) | TSHRCASP1PDE10AMAPTKDM4E | |
| SCHEMBL12428625 | 0.79 | L3MBTL1 (0.46) | TSHRCASP1PDE10AMAPTKDM4E | |
| SCHEMBL12277454 | 0.78 | PDE10A (0.61) | TSHRCASP1PDE10AMAPTKDM4E | |
| SCHEMBL10494914 | 0.77 | TDP1 (0.57) | TSHRCASP1PDE10AMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL11787488 | 0.76 | TDP1 (0.56) | TSHRCASP1PDE10AMAPTKDM4E | |
| SCHEMBL11511659 | 0.76 | ALDH1A1 (0.44) | TSHRCASP1PDE10AMAPTKDM4E | |
| SCHEMBL9645581 | 0.76 | CASP1 (0.58) | TSHRCASP1PDE10AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4170452-A | Dye composition containing diphenylamine and polyhydroxybenzene | L'OREAL (FR) | 1979-10-09 | — | — | US | disclosed |