Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276526 | 0.92 | CA2 (0.48) | CA2CA1CPB2MAPK1ALDH1A1 | |
| SCHEMBL11276531 | 0.92 | CA2 (0.48) | CA2CA1CPB2MAPK1ALDH1A1 | |
| SCHEMBL32677990 | 0.90 | ALDH1A1 (0.46) | CPB2ALDH1A1TRPA1MEN1NPC1 | |
| SCHEMBL32677989 | 0.90 | ALDH1A1 (0.46) | CPB2ALDH1A1TRPA1MEN1NPC1 | |
| SCHEMBL5491480 | 0.90 | CA2 (0.57) | CA2CA1CPB2MAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27486062 | 0.88 | CA2 (0.55) | CA2CA1CPB2MAPK1ALDH1A1 | |
| SCHEMBL21052329 | 0.88 | CA2 (0.55) | CA2CA1CPB2MAPK1ALDH1A1 | |
| SCHEMBL28301437 | 0.88 | CA2 (0.55) | CA2CA1CPB2MAPK1ALDH1A1 | |
| SCHEMBL28652592 | 0.86 | CA2 (0.50) | CA2CA1CPB2MAPK1ALDH1A1 | |
| SCHEMBL18837210 | 0.86 | CA2 (0.53) | CA2CA1CPB2MAPK1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086052-A | Antiarthritic, antiallergens, antiinflammatory agents; also for asthma and psoriasis | ABBOTT LABORATORIES (US) | 1992-02-04 | — | — | US | disclosed |
| US-4970210-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1990-11-13 | — | — | US | disclosed |