Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10701243 | 0.84 | MAOA (0.42) | CES2CES1PTGS2MAOAMAOB | |
| SCHEMBL28526172 | 0.82 | MAOA (0.47) | CES2CES1MAOAMAOBNPSR1 | |
| SCHEMBL28538201 | 0.81 | RECQL (0.49) | CES2CES1NAAATDP1 | |
| SCHEMBL31252725 | 0.80 | KMT2A (0.38) | MAOAMAOBNPSR1 | |
| SCHEMBL9436499 | 0.79 | MAOA (0.39) | CES1MAOAMAOBNPSR1TDP1 | |
| SCHEMBL3730655 | 0.77 | RECQL (0.47) | CES2CES1NAAATDP1 | |
| SCHEMBL15413487 | 0.74 | MAOA (0.44) | PTGS2MAOAMAOBNPSR1 | |
| SCHEMBL9498520 | 0.74 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL20448 | 0.72 | PTGS2 (0.57) | CES2CES1PTGS2NAAAMAOA | |
| SCHEMBL2866425 | 0.72 | MAOA (0.45) | CES2CES1MAOAMAOBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5123953-A | DIHALOGENATED HERBICIDAL SULPHONES | RHONE-POULENC AGROCHIMIE (FR) | 1992-06-23 | — | — | US | disclosed |
| EP-0398818-A1 | Dihalogenated herbicidal sulfones | RHONE-POULENC AGROCHIMIE (FR) | 1990-11-22 | — | — | EP | disclosed |