Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.94 |
| ▸ | MEN1 | O00255 | 4/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.85 |
| ▸ | LMNA | P02545 | 3/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.85 |
| ▸ | TSHR | P16473 | 1/20 | 0.85 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.85 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.75 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.75 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.74 |
| ▸ | CA12 | O43570 | 1/20 | 0.72 |
| ▸ | CA1 | P00915 | 1/20 | 0.72 |
| ▸ | CA2 | P00918 | 1/20 | 0.72 |
| ▸ | CA7 | P43166 | 1/20 | 0.72 |
| ▸ | CA9 | Q16790 | 1/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.72 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1019998 | 1.00 | KDM4E (0.94) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13149349 | 0.91 | KDM4E (0.78) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4486386 | 0.91 | KDM4E (0.78) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4515670 | 0.89 | KDM4E (0.76) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL4516322 | 0.89 | KDM4E (0.76) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL25041158 | 0.89 | KDM4E (0.76) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL20121634 | 0.89 | KDM4E (0.76) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7474168 | 0.89 | KDM4E (0.76) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL17696082 | 0.89 | KDM4E (0.76) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL12452433 | 0.89 | ALDH1A1 (0.76) | KDM4EALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255471-B1 | 1,4,7,10-TETRAAZACYCLODODECANE-DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-09-09 | — | — | EP | disclosed |