Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.49 |
| ▸ | S100A10 | P60903 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1346857 | 0.86 | HTR6 (0.58) | GAAMAPTKDM4ESERPINE1POLB | |
| SCHEMBL10608105 | 0.84 | HTR6 (0.59) | BCL2MCL1ANXA2S100A10GAA | |
| SCHEMBL10608103 | 0.84 | HTR6 (0.59) | BCL2MCL1ANXA2S100A10GAA | |
| SCHEMBL10948877 | 0.84 | HTR6 (0.59) | BCL2MCL1ANXA2S100A10GAA | |
| SCHEMBL9625568 | 0.82 | HTR6 (0.64) | BCL2MCL1ANXA2S100A10MAPT | |
| SCHEMBL9646750 | 0.80 | SERPINE1 (0.50) | MCL1GAAMAPTSERPINE1POLB | |
| SCHEMBL30110766 | 0.80 | SERPINE1 (0.64) | GAAMAPTKDM4ESERPINE1POLB | |
| SCHEMBL30320261 | 0.80 | SERPINE1 (0.64) | GAAMAPTKDM4ESERPINE1POLB | |
| SCHEMBL1097599 | 0.80 | SERPINE1 (0.64) | GAAMAPTKDM4ESERPINE1POLB | |
| SCHEMBL9646248 | 0.79 | MAPT (0.52) | MCL1GAAMAPTSERPINE1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213454-B1 | HEAT SENSITIVE RECORDING SHEETS CONTAINING SULFONE DERIVATIVES | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1992-12-02 | — | — | EP | claimed |
| US-5043313-A | Mixture of leuco dye and diphenyl polyhydroxy sulfone compound | RICOH COMPANY, LTD. (JP) | 1991-08-27 | — | — | US | claimed |
| US-4729984-A | CHROMOGENS | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-03-08 | — | — | US | claimed |
| EP-0213454-A2 | Heat sensitive recording sheets containing sulfone derivatives | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-03-11 | — | — | EP | claimed |
| EP-0213454-B1 | HEAT SENSITIVE RECORDING SHEETS CONTAINING SULFONE DERIVATIVES | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1992-12-02 | — | — | EP | disclosed |
| US-5043313-A | Mixture of leuco dye and diphenyl polyhydroxy sulfone compound | RICOH COMPANY, LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| US-4729984-A | CHROMOGENS | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-03-08 | — | — | US | disclosed |
| EP-0213454-A2 | Heat sensitive recording sheets containing sulfone derivatives | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-03-11 | — | — | EP | disclosed |