Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SERPINE1 | P05121 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13026657 | 0.82 | TSHR (0.59) | MAPTGAATSHRALDH1A1KMT2A | |
| SCHEMBL30320261 | 0.82 | SERPINE1 (0.64) | MAPTGAASERPINE1ALDH1A1HSD17B10 | |
| SCHEMBL1097599 | 0.82 | SERPINE1 (0.64) | MAPTGAASERPINE1ALDH1A1HSD17B10 | |
| SCHEMBL30110766 | 0.82 | SERPINE1 (0.64) | MAPTGAASERPINE1ALDH1A1HSD17B10 | |
| SCHEMBL9647745 | 0.81 | GAA (0.47) | MAPTGAASERPINE1ALDH1A1HSD17B10 | |
| SCHEMBL312194 | 0.79 | GAA (0.64) | MAPTGAASERPINE1ALDH1A1KMT2A | |
| SCHEMBL9645858 | 0.79 | BCL2 (0.51) | MAPTGAASERPINE1MCL1ALDH1A1 | |
| SCHEMBL1347993 | 0.79 | SERPINE1 (0.55) | MAPTGAASERPINE1ALDH1A1POLB | |
| SCHEMBL34461892 | 0.79 | SERPINE1 (0.55) | MAPTGAASERPINE1ALDH1A1POLB | |
| SCHEMBL1346857 | 0.77 | HTR6 (0.58) | MAPTGAASERPINE1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213454-B1 | HEAT SENSITIVE RECORDING SHEETS CONTAINING SULFONE DERIVATIVES | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1992-12-02 | — | — | EP | claimed |
| US-5043313-A | Mixture of leuco dye and diphenyl polyhydroxy sulfone compound | RICOH COMPANY, LTD. (JP) | 1991-08-27 | — | — | US | claimed |
| US-4729984-A | CHROMOGENS | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-03-08 | — | — | US | claimed |
| EP-0213454-A2 | Heat sensitive recording sheets containing sulfone derivatives | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-03-11 | — | — | EP | claimed |
| EP-0213454-B1 | HEAT SENSITIVE RECORDING SHEETS CONTAINING SULFONE DERIVATIVES | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1992-12-02 | — | — | EP | disclosed |
| US-5043313-A | Mixture of leuco dye and diphenyl polyhydroxy sulfone compound | RICOH COMPANY, LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| US-4729984-A | CHROMOGENS | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-03-08 | — | — | US | disclosed |
| EP-0213454-A2 | Heat sensitive recording sheets containing sulfone derivatives | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-03-11 | — | — | EP | disclosed |