Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.51 |
| ▸ | GABRP | O00591 | 4/20 | 0.50 |
| ▸ | GABRD | O14764 | 4/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.50 |
| ▸ | GABRE | P78334 | 4/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645197 | 0.78 | ALOX5 (0.51) | CRBNALOX5GABRPGABRDGABRA1 | |
| SCHEMBL21047882 | 0.73 | ELANE (0.50) | CRBNGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21047790 | 0.72 | CRBN (0.54) | CRBNGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL9645827 | 0.71 | ALOX5 (0.54) | CRBNALOX5HTR3AHTT | |
| SCHEMBL30903262 | 0.71 | ELANE (0.57) | CRBNCHRNA7HTR3AELANELMNA | |
| SCHEMBL5021493 | 0.71 | ELANE (0.61) | CRBNCHRNA7HTR3AELANELMNA | |
| SCHEMBL31472604 | 0.71 | ELANE (0.61) | CRBNCHRNA7HTR3AELANELMNA | |
| SCHEMBL9645891 | 0.70 | GABRP (0.48) | CRBNGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21047659 | 0.70 | CRBN (0.52) | CRBNGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL5021503 | 0.69 | ELANE (0.62) | CRBNGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086052-A | Antiarthritic, antiallergens, antiinflammatory agents; also for asthma and psoriasis | ABBOTT LABORATORIES (US) | 1992-02-04 | — | — | US | disclosed |
| US-4970210-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1990-11-13 | — | — | US | disclosed |
| EP-0299449-A2 | Pyridazinone, triazinone and oxapyridazinone lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1989-01-18 | — | — | EP | disclosed |