Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4190771 | 0.82 | CA2 (0.47) | CA2APLNR | |
| SCHEMBL1473224 | 0.82 | CA2 (0.47) | CA2APLNR | |
| SCHEMBL4191651 | 0.82 | CA2 (0.47) | CA2APLNR | |
| SCHEMBL9645747 | 0.78 | PYCR1 (0.38) | CA2APLNR | |
| SCHEMBL9644866 | 0.77 | CYP1A2 (0.33) | CA2 | |
| SCHEMBL5734584 | 0.72 | CA2 (0.40) | CA2APLNR | |
| SCHEMBL5732344 | 0.71 | CA2 (0.39) | CA2APLNR | |
| SCHEMBL14510201 | 0.70 | CA2 (0.48) | CA2 | |
| SCHEMBL1931055 | 0.69 | CYP1A2 (0.38) | CA2APLNR | |
| SCHEMBL1931051 | 0.69 | CYP1A2 (0.38) | CA2APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296580-B1 | PHENYLENE, FURYL, AND THIENYL LEUKOTRIENE B4 ANALOGUES | G.D. Searle & Co. (US) | 1992-11-11 | — | — | EP | disclosed |
| US-4895869-A | ANTIINFLAMMATORY | C. D. SEARLE & CO. (US) | 1990-01-23 | — | — | US | disclosed |
| EP-0296580-A2 | Phenylene, furyl, and thienyl leukotriene B4 analogues | G.D. Searle & Co. (US) | 1988-12-28 | — | — | EP | disclosed |
| US-4791133-A | ANTIINFLAMMATORY AGENTS | G. D. SEARLE & CO. (US) | 1988-12-13 | — | — | US | disclosed |