Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | GPX4 | P36969 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9649069 | 0.94 | PIN1 (0.34) | RAB9ANPC1PAX8JAK2ALDH1A1 | |
| SCHEMBL9160814 | 0.94 | PIN1 (0.35) | RAB9ANPC1PAX8JAK2ALDH1A1 | |
| SCHEMBL8430751 | 0.87 | KDM5A (0.38) | SRD5A1EPHX2 | |
| SCHEMBL10373067 | 0.87 | PIN1 (0.38) | PIN1ALOX15 | |
| SCHEMBL28398905 | 0.84 | ADH1C (0.35) | ALDH1A1ADH1CADH1AADH4EPHX2 | |
| SCHEMBL28400870 | 0.84 | ADH1C (0.35) | ALDH1A1ADH1CADH1AADH4EPHX2 | |
| SCHEMBL28402797 | 0.84 | ADH1C (0.35) | ALDH1A1ADH1CADH1AADH4EPHX2 | |
| SCHEMBL28406578 | 0.84 | ADH1C (0.35) | ALDH1A1ADH1CADH1AADH4EPHX2 | |
| SCHEMBL28401521 | 0.84 | ADH1C (0.35) | ALDH1A1ADH1CADH1AADH4EPHX2 | |
| SCHEMBL9160869 | 0.84 | PIN1 (0.38) | ALDH1A1PIN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153907-B1 | COMPOUNDS CONTAINING PIPERIDINE AND THEIR USE IN THE STABILISATION OF SYNTHETIC POLYMERS | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | disclosed |
| US-4618634-A | 2,2,6,6-TETRAMETHYLPIPERIDIN-4YL)ALKOXY-AMIDES | CIBA-GEIGY S.P.A. (IT) | 1986-10-21 | — | — | US | disclosed |
| EP-0153907-A2 | Compounds containing piperidine and their use in the stabilisation of synthetic polymers | CIBA-GEIGY AG (CH) | 1985-09-04 | — | — | EP | disclosed |