Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19246201 | 0.90 | HPGD (0.64) | CTSDHPGDHTTALDH1A1MEN1 | |
| SCHEMBL9645150 | 0.82 | CHRNB2 (0.61) | CTSDHPGDHTTALDH1A1MEN1 | |
| SCHEMBL29508722 | 0.81 | HPGD (0.79) | HPGDHTTALDH1A1KDM4ERCE1 | |
| SCHEMBL19246188 | 0.81 | KMT2A (0.75) | CTSDHPGDHTTALDH1A1MEN1 | |
| SCHEMBL30236290 | 0.81 | KMT2A (0.75) | CTSDHPGDHTTALDH1A1MEN1 | |
| SCHEMBL10602289 | 0.79 | CTSD (0.70) | CTSDHPGDHTTALDH1A1KDM4E | |
| SCHEMBL3943929 | 0.78 | HDAC2 (0.67) | HPGDHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL962966 | 0.78 | CTSD (1.00) | CTSDHPGDHTTALDH1A1KDM4E | |
| SCHEMBL22163884 | 0.78 | CTSD (0.69) | CTSDHPGDHTTALDH1A1KDM4E | |
| SCHEMBL9647861 | 0.77 | HPGD (0.65) | CTSDHPGDHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | disclosed |
| EP-0284174-A1 | Therapeutic preparations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-28 | — | — | EP | disclosed |