Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KCNJ6 | P48051 | 7/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 7/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 6/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.33 |
| ▸ | FEN1 | P39748 | 3/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11394393 | 0.88 | ALDH1A1 (0.41) | ALDH1A1KCNJ6KCNJ3KCNJ5ALOX5AP | |
| SCHEMBL10426108 | 0.74 | ALDH1A1 (0.39) | ALDH1A1CYP3A4ALOX15TSHRBLM | |
| SCHEMBL9646033 | 0.72 | MEN1 (0.38) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8658209 | 0.69 | ALDH1A1 (0.41) | ALDH1A1CYP3A4ALOX15TSHRBLM | |
| SCHEMBL11338630 | 0.69 | CA1 (0.41) | ALDH1A1CYP3A4ALOX15TSHRBLM | |
| SCHEMBL29451981 | 0.67 | ALDH1A1 (0.42) | ALDH1A1KCNJ6KCNJ3KCNJ5ALOX5AP | |
| SCHEMBL15094272 | 0.67 | KCNJ6 (0.36) | ALDH1A1KCNJ6KCNJ3KCNJ5PIK3C3 | |
| SCHEMBL9397362 | 0.66 | ALDH1A1 (0.64) | ALDH1A1CYP3A4ALOX15TSHRBLM | |
| SCHEMBL22909297 | 0.65 | HDAC6 (0.42) | ALDH1A1ALOX5APFEN1CYP3A4ALOX15 | |
| SCHEMBL16176976 | 0.65 | CA1 (0.39) | ALDH1A1TSHRKDM4EMAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106960-A | Fiber-reactive and monoazo red and yellow dyes; color- and washfastness; formaldehyde-resistance; brightness | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0039306-B1 | AZO DYESTUFFS, METHODS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1984-01-11 | — | — | EP | disclosed |