Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271530 | 0.79 | G6PD (0.55) | G6PDGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7975058 | 0.76 | G6PD (0.56) | G6PDGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9849787 | 0.73 | G6PD (0.64) | G6PDGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9007793 | 0.73 | G6PD (0.50) | G6PDGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27913504 | 0.73 | AR (0.51) | GAAMAPTSMN1; SMN2 | |
| SCHEMBL17548921 | 0.72 | G6PD (0.63) | G6PDGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL271985 | 0.72 | G6PD (0.67) | G6PDGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6930692 | 0.71 | G6PD (0.51) | G6PDGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5177925 | 0.71 | G6PD (0.51) | G6PDGAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8372106 | 0.71 | G6PD (0.51) | G6PDGAAALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086052-A | Antiarthritic, antiallergens, antiinflammatory agents; also for asthma and psoriasis | ABBOTT LABORATORIES (US) | 1992-02-04 | — | — | US | disclosed |
| US-4970210-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1990-11-13 | — | — | US | disclosed |