Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647022 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TDP1MEN1POLB | |
| SCHEMBL9647010 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TDP1MEN1POLB | |
| SCHEMBL9648296 | 0.95 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1TDP1MEN1POLB | |
| SCHEMBL9648285 | 0.95 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1TDP1MEN1POLB | |
| SCHEMBL9648304 | 0.95 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1TDP1MEN1POLB | |
| SCHEMBL9647334 | 0.92 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1MEN1POLBKMT2A | |
| SCHEMBL9647339 | 0.92 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1MEN1POLBKMT2A | |
| SCHEMBL9647325 | 0.92 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1MEN1POLBKMT2A | |
| SCHEMBL9647275 | 0.92 | CYP1A2 (0.42) | SMN1; SMN2ALDH1A1MEN1POLBKMT2A | |
| SCHEMBL9647270 | 0.92 | CYP1A2 (0.42) | SMN1; SMN2ALDH1A1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102578-A | Electrooptics | HOFFMANN-LA ROCHE INC. (US) | 1992-04-07 | — | — | US | disclosed |