Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9648304 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL9648296 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL9647022 | 0.95 | SMN1; SMN2 (0.41) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL9647016 | 0.95 | SMN1; SMN2 (0.41) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL9647010 | 0.95 | SMN1; SMN2 (0.41) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL9645661 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL9645670 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL9645666 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL9406915 | 0.90 | ALDH1A1 (0.41) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL9647482 | 0.90 | ALDH1A1 (0.41) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102578-A | Electrooptics | HOFFMANN-LA ROCHE INC. (US) | 1992-04-07 | — | — | US | disclosed |