Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPEP1 | P16444 | 10/20 | 0.44 |
| ▸ | LAP3 | P28838 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9647029 | 1.00 | DPEP1 (0.44) | DPEP1LAP3METAP1ALDH1A1KMT2A | |
| SCHEMBL9646250 | 0.82 | GRIK1 (0.47) | DPEP1LAP3ALDH1A1GRIK1 | |
| SCHEMBL9646228 | 0.82 | GRIK1 (0.47) | DPEP1LAP3ALDH1A1GRIK1 | |
| SCHEMBL9646018 | 0.82 | DPEP1 (0.63) | DPEP1METAP1GRIK1 | |
| SCHEMBL9647109 | 0.82 | DPEP1 (0.63) | DPEP1METAP1GRIK1 | |
| SCHEMBL9645166 | 0.82 | DPEP1 (0.63) | DPEP1METAP1GRIK1 | |
| SCHEMBL9646476 | 0.81 | LAP3 (0.49) | LAP3GRIK1 | |
| SCHEMBL9646542 | 0.81 | LAP3 (0.49) | LAP3GRIK1 | |
| SCHEMBL9645188 | 0.81 | DPEP1 (0.56) | DPEP1METAP1ALDH1A1KMT2AGRIK1 | |
| SCHEMBL9647037 | 0.81 | DPEP1 (0.56) | DPEP1METAP1ALDH1A1KMT2AGRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366469-A2 | Phosphorus containing enzyme inhibitors | MERCK & CO. INC. (US) | 1990-05-02 | — | — | EP | claimed |
| US-5147867-A | Bactericides, (carba)penicillins | MERCK & CO., INC. (US) | 1992-09-15 | — | — | US | disclosed |
| US-5145990-A | Dehydropeptidase, carbapenicillin potentiation | MERCK & CO., INC. (US) | 1992-09-08 | — | — | US | disclosed |
| US-4962097-A | IN COMBINATION WITH A CARBAPENEM OR PENEM ANTIBIOTIC | MERCK & CO., INC. (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0366469-A2 | Phosphorus containing enzyme inhibitors | MERCK & CO. INC. (US) | 1990-05-02 | — | — | EP | disclosed |