SCHEMBL964759

SCHEMBL964759

C=CC1=NCCCC(=O)O1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL541886 0.89
SCHEMBL966568 0.76
SCHEMBL676811 0.67
SCHEMBL11060608 0.66 TSHR (0.30) TSHR
SCHEMBL9864890 0.64 TSHR (0.32) TSHR
SCHEMBL252015 0.62
SCHEMBL23754669 0.62 TSHR (0.71) TSHR
SCHEMBL320487 0.62
SCHEMBL19926 0.62
Acrylic Acid SCHEMBL10715123 0.61 LMNA (0.46) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11279731-B2 Ligand functional substrates 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-03-22 US disclosed
US-11111320-B2 Addition-fragmentation oligomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-09-07 US disclosed
EP-3326711-B1 GRAFT COPOLYMER FUNCTIONALIZED ARTICLE 3M INNOVATIVE PROPERTIES CO (US) 2021-07-07 EP disclosed
CN-107406723-B Addition-fragmentation oligomers 3M创新有限公司 2021-05-07 CN disclosed
EP-2675783-B1 ADDITION-FRAGMENTATION AGENTS 3M INNOVATIVE PROPERTIES CO (US) 2020-04-22 EP disclosed
EP-3259323-B1 ADDITION-FRAGMENTATION OLIGOMERS 3M INNOVATIVE PROPERTIES CO (US) 2020-02-26 EP disclosed
US-20200031961-A1 ADDITION-FRAGMENTATION OLIGOMERS 3M INNOVATIVE PROPERTIES CO (US) 2020-01-30 US disclosed
US-10479848-B2 Addition-fragmentation oligomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-11-19 US disclosed
US-10471398-B2 Graft copolymer functionalized article 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-11-12 US disclosed
US-10370322-B2 Addition-fragmentation agents 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-08-06 US disclosed
EP-0808348-A1 PROCESS FOR THE PRODUCTION OF AN ARTICLE COATED WITH A CROSSLINKED PRESSURE SENSITIVE ADHESIVE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-11-26 EP disclosed
WO-1996024644-A1 PROCESS FOR THE PRODUCTION OF AN ARTICLE COATED WITH A CROSSLINKED PRESSURE SENSITIVE ADHESIVE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-15 WO disclosed
US-4996243-A 2-Alkenyl-5,6-dihydro-4H-1,3-oxazin-6-one-modified polymers and a photoinitiator; adhesives; films; inks; coatings; and saturants MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-02-26 US disclosed
US-4914223-A Coatings, films, printing inks, adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-04-03 US disclosed
US-4837290-A REACTING ALKENYL AZLACTONE WITH POLYMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-06-06 US disclosed
US-4777276-A COATINGS, FILMS, PRINTING INKS AND ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-10-11 US disclosed
EP-0091956-B1 ACRYLAMIDOACYLATED OLIGOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-02-26 EP disclosed
EP-0091956-A4 ACRYLAMIDOACYLATED OLIGOMERS. MINNESOTA MINING & MFG (US) 1984-04-24 EP disclosed
EP-0091956-A1 ACRYLAMIDOACYLATED OLIGOMERS. MINNESOTA MINING & MFG (US) 1983-10-26 EP disclosed
WO-1983001617-A1 ACRYLAMIDOACYLATED OLIGOMERS MINNESOTA MINING & MFG (US) 1983-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10479848-B2 Addition-fragmentation oligomers ECPAS, ITGA8, NBAS TSHR 4794/4885NOS3 3403/4885NOS1 4257/4885
US-10370322-B2 Addition-fragmentation agents NR4A1, PARP14, MTX1 TSHR 1778/4885NOS3 3937/4885NOS1 3814/4885
US-20200031961-A1 ADDITION-FRAGMENTATION OLIGOMERS ECPAS, ITGA8, NBAS TSHR 4794/4885NOS3 3403/4885NOS1 4257/4885
US-11279731-B2 Ligand functional substrates PCNA, POLM, POLL TSHR 4365/4885NOS3 4435/4885NOS1 4321/4885
US-11111320-B2 Addition-fragmentation oligomers ECPAS, ITGA8, NBAS TSHR 4794/4885NOS3 3403/4885NOS1 4257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.