Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28264960 | 0.81 | CHRM1 (0.57) | ACHEBCHECHRM1CHRM3CHRM2 | |
| SCHEMBL4172713 | 0.79 | KMT2A (0.45) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL2496049 | 0.79 | MMP2 (0.44) | ACHEBCHECHRM1CHRM3CHRM2 | |
| SCHEMBL1395108 | 0.79 | HTR2A (0.36) | — | |
| Bicarbonate SCHEMBL9647641 | 0.78 | CA1 (0.44) | CHRNA7CHRNB4CHRNA3SMN1; SMN2CHRNA10 | |
| SCHEMBL609104 | 0.78 | CA1 (0.48) | SMN1; SMN2MAPTLMNARAB9A | |
| SCHEMBL6708532 | 0.78 | MMP2 (0.43) | ACHEBCHECHRM1CHRM3CHRM2 | |
| Bicarbonate SCHEMBL9647679 | 0.77 | CHRNA7 (0.45) | CHRNA7CHRNB4CHRNA3SMN1; SMN2CHRNA10 | |
| Bicarbonate SCHEMBL9647658 | 0.77 | CHRNB4 (0.45) | CHRNA7CHRNB4CHRNA3SMN1; SMN2CHRNA10 | |
| SCHEMBL8662964 | 0.77 | HTR2A (0.54) | SMN1; SMN2MAPTLMNAGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082964-A | Selective acetylcholinesterase inhibitors and methods of making and using same | LEHIGH UNIVERSITY (US) | 1992-01-21 | — | — | US | disclosed |