Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 2/20 | 0.64 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.64 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.48 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | PRKCG | P05129 | 1/20 | 0.48 |
| ▸ | PRKCB | P05771 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | PRKACG | P22612 | 1/20 | 0.48 |
| ▸ | PRKACB | P22694 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | PRKCH | P24723 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17506602 | 0.82 | IMPDH2 (0.69) | IMPDH2IMPDH1PRKD3CCNB2CCNE2 | |
| SCHEMBL30277938 | 0.78 | IMPDH2 (0.64) | IMPDH2IMPDH1PRKD3CCNB2CCNE2 | |
| SCHEMBL5130557 | 0.78 | IMPDH2 (0.64) | IMPDH2IMPDH1PRKD3CCNB2CCNE2 | |
| SCHEMBL186741 | 0.78 | IMPDH2 (1.00) | IMPDH2IMPDH1PRKD3CCNB2CCNE2 | |
| SCHEMBL3769477 | 0.78 | IMPDH2 (0.64) | IMPDH2IMPDH1PRKD3CCNB2CCNE2 | |
| SCHEMBL1752696 | 0.78 | IMPDH2 (0.64) | IMPDH2IMPDH1PRKD3CCNB2CCNE2 | |
| SCHEMBL29820843 | 0.78 | IMPDH2 (1.00) | IMPDH2IMPDH1PRKD3CCNB2CCNE2 | |
| SCHEMBL7237886 | 0.78 | IMPDH2 (0.64) | IMPDH2IMPDH1PRKD3CCNB2CCNE2 | |
| SCHEMBL4736533 | 0.78 | IMPDH2 (0.64) | IMPDH2IMPDH1PRKD3CCNB2CCNE2 | |
| Hydrochloric Acid SCHEMBL7697252 | 0.77 | IMPDH2 (0.96) | IMPDH2IMPDH1PRKD3CCNB2CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925369-B | Beta-carboline cyano furan derivatives, preparation method and application thereof | 南通大学 | 2021-09-28 | — | — | CN | claimed |
| WO-2020231766-A1 | AGONISTS OF ROR GAMMAt | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-11-19 | — | — | WO | claimed |
| CN-111925369-A | Beta-carboline cyano furan derivatives, preparation method and application thereof | 南通大学 | 2020-11-13 | — | — | CN | claimed |
| CN-108026073-A | Fluoroindole derivatives as muscarinic M 1 receptor forward direction allosteric modulators | 苏文生命科学有限公司 | 2018-05-11 | — | — | CN | claimed |
| US-7994335-B2 | Electronically tuned ligands for asymmetric hydrogenation | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-09 | — | — | US | claimed |
| US-20100041898-A1 | Electronically Tuned Ligands For Asymmetric Hydrogenation | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-18 | — | — | US | claimed |
| US-20090022729-A1 | METHODS AND COMPOSITIONS FOR TREATING CARDIAC DYSFUNCTIONS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-01-22 | — | — | US | claimed |
| WO-2008128038-A2 | METHODS AND COMPOSITIONS FOR TREATING CARDIAC DYSFUNCTIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-10-23 | — | — | WO | claimed |
| WO-2008067218-A1 | ELECTRONICALLY TUNED LIGANDS FOR ASYMMETRIC HYDROGENATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-06-05 | — | — | WO | claimed |
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |
| EP-0676411-A2 | Peptides and pseudopeptides derived from tachykinine, their preparation and their pharmaceutical compositions | ADIR ET COMPAGNIE (FR) | 1995-10-11 | — | — | EP | claimed |
| EP-0517589-A2 | Tachykinin derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-12-09 | — | — | EP | claimed |
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | claimed |
| EP-0480918-A1 | REDUCED SIZE LHRH ANALOGS | ABBOTT LABORATORIES (US) | 1992-04-22 | — | — | EP | claimed |
| EP-0429984-A2 | Indole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-06-05 | — | — | EP | claimed |
| EP-0480918-A4 | REDUCED SIZE LHRH ANALOGS. | ABBOTT LAB (US) | 1991-06-04 | — | — | EP | claimed |
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | claimed |
| WO-1989007451-A1 | REDUCED SIZE LHRH ANALOGS | ABBOTT LABORATORIES (US) | 1989-08-24 | — | — | WO | claimed |
| EP-0328089-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | claimed |
| US-3980667-A | Anti-arrhythmic 5-endo-substituted oxy-N-(aminoloweralkyl)bicycle [2.2.2.]oc | BRISTOL-MYERS COMPANY (US) | 1976-09-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041898-A1 | Electronically Tuned Ligands For Asymmetric Hydrogenation | BID, HDHD5, HRH4 | IMPDH2 2561/4885IMPDH1 3359/4885PRKD3 3586/4885 |
| US-20090022729-A1 | METHODS AND COMPOSITIONS FOR TREATING CARDIAC DYSFUNCTIONS | TNNI3, MYLK2, FABP3 | IMPDH2 3325/4885IMPDH1 2934/4885PRKD3 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.