Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15920931 | 0.86 | S1PR1 (0.38) | — | |
| SCHEMBL3315633 | 0.85 | FFAR3 (0.34) | FFAR3 | |
| SCHEMBL7154976 | 0.85 | FFAR3 (0.34) | FFAR3 | |
| SCHEMBL8894488 | 0.78 | BDKRB2 (0.35) | BDKRB2PARP1 | |
| SCHEMBL8894194 | 0.78 | BDKRB2 (0.35) | BDKRB2PARP1 | |
| SCHEMBL21618645 | 0.76 | HSD11B1 (0.37) | FFAR3TSHRCYP2C19 | |
| SCHEMBL2275708 | 0.74 | FFAR3 (0.39) | FFAR3TSHRNFKB1CYP2C19 | |
| SCHEMBL369709 | 0.74 | FFAR3 (0.39) | FFAR3TSHRNFKB1CYP2C19 | |
| SCHEMBL359077 | 0.74 | FFAR3 (0.39) | FFAR3TSHRNFKB1CYP2C19 | |
| SCHEMBL24858609 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253785-B1 | EFFICIENT STEREOCONSERVATIVE SYNTHESES OF 1-SUBSTITUTED (S)- AND (R)-2-AMINOMETHYLPYRROLIDINES AND INTERMEDIATES THEREIN | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1992-11-11 | — | — | EP | claimed |