SCHEMBL9649205

SCHEMBL9649205

COCC(CCO)CCO

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19333803 0.90 ALDH1A1 (0.30)
SCHEMBL12436582 0.89
SCHEMBL13553143 0.80 GBA1 (0.31) ROCK2
SCHEMBL17526693 0.76 ALDH1A1 (0.37) THRB
SCHEMBL17526685 0.76 ALDH1A1 (0.37) THRB
SCHEMBL1079107 0.75
SCHEMBL2989955 0.75
SCHEMBL12766253 0.75
SCHEMBL316627 0.74
SCHEMBL11276459 0.74 ROCK2 (0.30) ROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5108652-A Liquid crystal dielectrics Merck patent Gesellschaft mit beschrankter Haftung Darmstadt (DE) 1992-04-28 US disclosed
US-4986931-A Cyclohexane derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-01-22 US disclosed
US-4510069-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1985-04-09 US disclosed
EP-0107759-A2 Cyclohexane derivatives and their use as components for liquid crystals MERCK PATENT GmbH (DE) 1984-05-09 EP disclosed