Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.77 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.77 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.77 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.77 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | PLK1 | P53350 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloralin SCHEMBL455937 | 0.87 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1HPGD | |
| SCHEMBL11211170 | 0.83 | ALDH1A1 (0.51) | CYP3A4ALDH1A1TSHRTDP1HPGD | |
| SCHEMBL7819749 | 0.82 | ALDH1A1 (0.82) | CYP3A4ALDH1A1TSHRTDP1HPGD | |
| SCHEMBL2415016 | 0.82 | ALDH1A1 (1.00) | CYP3A4ALDH1A1TSHRTDP1HPGD | |
| SCHEMBL10414958 | 0.81 | CYP3A4 (0.79) | CYP3A4ALDH1A1TSHRTDP1HPGD | |
| SCHEMBL11343876 | 0.81 | ALDH1A1 (0.79) | CYP3A4ALDH1A1TSHRTDP1HPGD | |
| SCHEMBL9015339 | 0.80 | ALDH1A1 (0.82) | CYP3A4ALDH1A1TSHRTDP1HPGD | |
| SCHEMBL17680884 | 0.79 | CYP3A4 (0.77) | CYP3A4ALDH1A1TSHRTDP1HPGD | |
| SCHEMBL205303 | 0.79 | ALDH1A1 (0.70) | CYP3A4ALDH1A1TSHRTDP1HPGD | |
| SCHEMBL10862632 | 0.79 | ALDH1A1 (0.77) | CYP3A4ALDH1A1TSHRTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107311873-B | Method for preparing 2, 6-dichloro-4-trifluoromethylaniline with 99% content | LIANYUNGANG AVILIVE CHEMICAL CO., LTD. (CN) | 2019-12-10 | — | — | CN | disclosed |
| EP-0280156-B1 | PROCESS FOR THE PREPARATION OF ACETOACETYLARYLAMIDES-HETEROARYLAMIDES RESPECTIVELY OF DEACTIVED AROMATIC COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0280156-A2 | Process for the preparation of acetoacetylarylamides-heteroarylamides respectively of deactived aromatic compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-31 | — | — | EP | disclosed |