Phosphoric Acid

Phosphoric Acid

SCHEMBL9649997

CCCCCCCCNC(C)(CCO)CCO.CCCCCCCCNC(C)(CCO)CCO.CCCCCCCCNC(C)(CCO)CCO.O=P(O)(O)O

nearest known ligand 0.43

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
S1PR2 O95136 5/20 0.43
S1PR4 O95977 5/20 0.43
S1PR1 P21453 5/20 0.43
S1PR3 Q99500 5/20 0.43
S1PR5 Q9H228 1/20 0.43
GGPS1 O95749 6/20 0.43
FDPS P14324 9/20 0.42
SMPD1 P17405 2/20 0.41
LPAR1 Q92633 1/20 0.41
LPAR3 Q9UBY5 1/20 0.41
NAAA Q02083 1/20 0.40
ANPEP P15144 1/20 0.39
ERAP2 Q6P179 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL9650783 1.00 S1PR2 (0.43) S1PR2S1PR4S1PR1S1PR3S1PR5
Phosphoric Acid SCHEMBL9649922 0.81 GGPS1 (0.46) S1PR2S1PR4S1PR1S1PR3S1PR5
SCHEMBL19353086 0.80 LMNA (0.50) NAAA
SCHEMBL21790560 0.79 LMNA (0.48) NAAA
Phosphoric Acid SCHEMBL28344522 0.79 S1PR2 (0.46) S1PR2S1PR4S1PR1S1PR3S1PR5
SCHEMBL19352786 0.78 LMNA (0.46) GGPS1FDPSNAAA
SCHEMBL18482260 0.77 EPHX1 (0.44)
SCHEMBL20643823 0.77 EPHX1 (0.44) GGPS1FDPS
SCHEMBL5052104 0.77 TDP1 (0.38)
SCHEMBL28182999 0.77 EPHX1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0332397-B1 FIBER-CONTAINING YARN POSSESSING ANTIMICROBIAL ACTIVITY BASF Corporation (US) 1992-11-25 EP claimed
EP-0332397-A2 Fiber-containing yarn possessing antimicrobial activity BASF Corporation (US) 1989-09-13 EP claimed
US-4842932-A MIXTURE OF FILAMENTS, A PORTION OF WHICH CONTAINS ANTIMICROBIAL AGENT BASF CORPORATION (US) 1989-06-27 US claimed
EP-0332397-B1 FIBER-CONTAINING YARN POSSESSING ANTIMICROBIAL ACTIVITY BASF Corporation (US) 1992-11-25 EP disclosed
EP-0332397-A2 Fiber-containing yarn possessing antimicrobial activity BASF Corporation (US) 1989-09-13 EP disclosed
US-4842932-A MIXTURE OF FILAMENTS, A PORTION OF WHICH CONTAINS ANTIMICROBIAL AGENT BASF CORPORATION (US) 1989-06-27 US disclosed