SCHEMBL9650265

SCHEMBL9650265

Clc1cccc(C2CC(c3ccccc3)=NN2c2ccccc2)c1

nearest known ligand 0.74

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.74
ATM Q13315 1/20 0.74
PRKCZ Q05513 4/20 0.73
MAOA P21397 2/20 0.71
MAOB P27338 2/20 0.71
EGFR P00533 6/20 0.71
ERBB2 P04626 5/20 0.65
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
ERBB3 P21860 1/20 0.56
KDR P35968 1/20 0.56
PTK2 Q05397 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2687815 0.89 PRKCZ (0.66) L3MBTL1ATMPRKCZMAOAMAOB
SCHEMBL2687670 0.88 PRKCZ (0.65) L3MBTL1ATMPRKCZMAOAMAOB
SCHEMBL27778542 0.86 EGFR (0.62) L3MBTL1ATMPRKCZMAOAMAOB
SCHEMBL18826392 0.86 L3MBTL1 (1.00) L3MBTL1ATMKMT2A
SCHEMBL23052404 0.85 MEN1 (0.73) L3MBTL1ATMPRKCZMAOAMAOB
SCHEMBL395608 0.85 MEN1 (0.73) L3MBTL1ATMPRKCZMAOAMAOB
SCHEMBL2688704 0.84 EGFR (0.62) L3MBTL1ATMPRKCZMAOAMAOB
SCHEMBL3896190 0.84 PRKCZ (0.82) L3MBTL1ATMPRKCZMAOAMAOB
SCHEMBL554670 0.84 EGFR (0.74) L3MBTL1ATMPRKCZMAOBEGFR
SCHEMBL16740583 0.83 PRKCZ (1.00) L3MBTL1ATMPRKCZMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0231835-B1 ELECTRO PHOTOGRAPHIC RECORDING MATERIAL HOECHST AKTIENGESELLSCHAFT (DE) 1992-11-11 EP disclosed
US-4762760-A FILM ON SUBSTRATE, ADHESION, FLEXIBILITY HOECHST AKTIENGESELLSCHAFT (DE) 1988-08-09 US disclosed
EP-0231835-A2 Electro photographic recording material HOECHST AKTIENGESELLSCHAFT (DE) 1987-08-12 EP disclosed