Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | AOC1 | P19801 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282388 | 0.76 | TSHR (0.45) | KDM4CCNR1CNR2GAABRS3 | |
| Hydrochloric Acid SCHEMBL9043124 | 0.75 | TSHR (0.44) | KDM4CCNR1CNR2GAABRS3 | |
| SCHEMBL5282911 | 0.74 | BRS3 (0.42) | KDM4CGAABRS3TSHRKMT2A | |
| SCHEMBL31576010 | 0.74 | TSHR (0.42) | TSHRALDH1A1AAK1NPC1RAB9A | |
| SCHEMBL9911853 | 0.70 | MAPT (0.46) | KDM4CTSHRAAK1NPC1RAB9A | |
| SCHEMBL1190850 | 0.70 | TSHR (0.49) | TSHRAAK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4153508 | 0.70 | TSHR (0.49) | TSHRAAK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9042912 | 0.70 | KDM6B (0.43) | KDM4CGAATSHRALDH1A1KMT2A | |
| SCHEMBL9659435 | 0.70 | ALDH1A1 (0.45) | TSHRALDH1A1KMT2ANPC1HTT | |
| SCHEMBL9039809 | 0.70 | BRS3 (0.47) | KDM4CBRS3TSHRALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480155-A2 | 4-Substituted dihydropyrido (4,3-d)pyrimidines as analgesics and topical antiinflammatory agents for the treatment of skin disorders | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-04-15 | — | — | EP | disclosed |