Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.43 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.43 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.43 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059606 | 1.00 | PYGB (0.55) | PYGBGAACA12CA1CA2 | |
| SCHEMBL12038703 | 0.98 | PYGB (0.58) | PYGBGAACA12CA1CA2 | |
| SCHEMBL19538490 | 0.98 | PYGB (0.58) | PYGBGAACA12CA1CA2 | |
| SCHEMBL14707760 | 0.98 | PYGB (0.58) | PYGBGAACA12CA1CA2 | |
| SCHEMBL1647661 | 0.98 | PYGB (0.58) | PYGBGAACA12CA1CA2 | |
| SCHEMBL1647658 | 0.98 | PYGB (0.58) | PYGBGAACA12CA1CA2 | |
| SCHEMBL3228008 | 0.98 | PYGB (0.58) | PYGBGAACA12CA1CA2 | |
| SCHEMBL18722237 | 0.98 | PYGB (0.58) | PYGBGAACA12CA1CA2 | |
| SCHEMBL23617758 | 0.80 | LGALS8 (0.53) | PYGBCA12CA1CA2CA9 | |
| SCHEMBL21698210 | 0.80 | LGALS8 (0.53) | PYGBCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516180-A1 | Novel sulfonamide derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-12-02 | — | — | EP | disclosed |
| EP-0516181-A1 | Novel sulfonamide derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-12-02 | — | — | EP | disclosed |
| US-5168101-A | Hypotensives, anticoagulants, cardiovascular and brain disorders | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-12-01 | — | — | US | disclosed |
| EP-0312906-A2 | Novel sulfonamide derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-04-26 | — | — | EP | disclosed |