Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22503904 | 0.83 | TSHR (0.39) | DNM1ALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL3677949 | 0.82 | ALDH1A1 (0.40) | DNM1ALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL2900295 | 0.81 | DNM1 (0.45) | DNM1 | |
| SCHEMBL253114 | 0.81 | TSHR (0.37) | DNM1ALDH1A1TSHR | |
| SCHEMBL27928001 | 0.79 | TSHR (0.36) | DNM1ALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL28151442 | 0.79 | TSHR (0.36) | DNM1ALDH1A1TSHR | |
| SCHEMBL27607732 | 0.79 | TSHR (0.36) | DNM1ALDH1A1TSHR | |
| SCHEMBL8093873 | 0.79 | DNM1 (0.43) | DNM1ALDH1A1 | |
| SCHEMBL31328392 | 0.78 | DNM1 (0.43) | DNM1KDM4ESMN1; SMN2TSHRLMNA | |
| SCHEMBL22877646 | 0.78 | KDM4E (0.40) | DNM1ALDH1A1KDM4ESMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091583-A | Also provides extended pot life | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1992-02-25 | — | — | US | disclosed |
| US-5071809-A | TERTIARY AMINE CATALYSTS FOR POLYURETHANES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0456194-A2 | Tertiary amine catalysts for polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-11-13 | — | — | EP | disclosed |