SCHEMBL9650550

SCHEMBL9650550

CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.36
CA2 P00918 2/20 0.33
CA1 P00915 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15325990 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL15326926 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL12522087 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL8723430 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL15325988 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL8740867 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL13881475 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL13881471 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL15325987 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL15325991 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230346989-A1 FLUOROCARBON NANOEMULSIONS AND USES THEREOF IN IMAGING THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-11-02 US disclosed
CN-112135888-A Curable composition, curable composition set, heat storage material, and article 昭和电工材料株式会社 2020-12-25 CN disclosed
WO-2013151697-A1 METHODS AND COMPOUNDS FOR IDENTIFYING GLYCOSYLTRANSFERASE INHIBITORS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-10-10 WO disclosed
WO-2013152279-A1 CHEMOENZYMATIC METHODS FOR SYNTHESIZING MOENOMYCIN ANALOGS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-10-10 WO disclosed
US-5142079-A Improve affinity between inorganic material and fluoropolymer AJINOMOTO CO., INC. (JP) 1992-08-25 US disclosed
EP-0432726-A1 Fluorinated carbon chain-containing aluminum surface modifier AJINOMOTO CO., INC. (JP) 1991-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230346989-A1 FLUOROCARBON NANOEMULSIONS AND USES THEREOF IN IMAGING NAF1, LIPA, SGMS1 LMNA 1197/4885THRB 4258/4885CA2 874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.