SCHEMBL8740867

SCHEMBL8740867

CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.36
CA2 P00918 2/20 0.33
CA1 P00915 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9650550 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL15325990 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL15326926 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL12522087 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL8723430 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL15325988 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL13881475 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL13881471 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL15325987 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1
SCHEMBL15325991 1.00 LMNA (0.44) LMNATHRBCA2CA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110761078-B Preparation method and application of black body material 中国科学技术大学 2021-04-23 CN claimed
CN-110761078-A Preparation method and application of black body material 中国科学技术大学 2020-02-07 CN claimed
US-20230400764-A1 ORGANOMETALLIC COMPOUND COMPRISING A METAL COMBINED WITH AT LEAST ONE LIGAND CONTAINING FOUR OR MORE FLUORINE ATOMS, RESIST COMPOSITION COMPRISING THE SAME, AND METHOD OF FABRICATING SEMICONDUCTOR DEVICE USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-12-14 US disclosed
US-20230240128-A1 COMPOUNDS FOR FORMING A PATTERNING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-07-27 US disclosed
US-11273583-B2 Polyorganosiloxane-based composition intended for tyre moulding/stripping ELKEM SILICONES FRANCE SAS (FR) 2022-03-15 US disclosed
WO-2021094588-A1 USE OF PERFLUORO-N-OCTANE FOR PIEZO-MEDIATED INTRACYTOPLASMIC SPERM INJECTION Vitrolife Sweden Aktiebolag (SE) 2021-05-20 WO disclosed
CN-110761078-B Preparation method and application of black body material 中国科学技术大学 2021-04-23 CN disclosed
US-10906908-B2 Ionic liquid, lubricating agent, and magnetic recording medium DEXERIALS CORPORATION (JP) 2021-02-02 US disclosed
CN-110761078-A Preparation method and application of black body material 中国科学技术大学 2020-02-07 CN disclosed
US-20180251468-A1 Ionic Liquid, Lubricating Agent, and Magnetic Recording Medium DEXERIALS CORP (JP) 2018-09-06 US disclosed
US-20150353558-A1 Ionic Liquid, Lubricating Agent, and Magnetic Recording Medium DEXERIALS CORPORATION (JP) 2015-12-10 US disclosed
US-7678918-B2 Intermediates for imidazonaphthyridines 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-03-16 US disclosed
US-20080091010-A1 Intermediates for imidazonaphthyridines GRACEWAY PHARMACEUTICALS, LLC (US) 2008-04-17 US disclosed
US-20080091010-A1 Intermediates for imidazonaphthyridines GRACEWAY PHARMACEUTICALS, LLC (US) 2008-04-17 US disclosed
US-7335773-B2 Intermediates for imidazonaphthyridines GRACEWAY PHARMACEUTICALS, LLC (US) 2008-02-26 US disclosed
US-7335773-B2 Intermediates for imidazonaphthyridines GRACEWAY PHARMACEUTICALS, LLC (US) 2008-02-26 US disclosed
US-20070167481-A1 IMIDAZONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES COMPANY 2007-07-19 US disclosed
US-20070167481-A1 IMIDAZONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES COMPANY 2007-07-19 US disclosed
US-5668251-A Preparation of co-prepolymers from mono-substituted fluorinated monomers and tetrahydrofuran AEROJET-GENERAL CORPORATION (US) 1997-09-16 US disclosed
EP-0151697-B1 METHOD FOR PURIFYING A MIXTURE OF PERFLUOROCARBONS ADAMANTECH, INC. (US) 1988-11-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080091010-A1 Intermediates for imidazonaphthyridines IFNG, IRF3, MAVS LMNA 2779/4885THRB 3595/4885CA2 4509/4885
US-10906908-B2 Ionic liquid, lubricating agent, and magnetic recording medium MUC1, JAK1, JAK3 LMNA 2468/4885THRB 3275/4885CA2 507/4885
US-20230240128-A1 COMPOUNDS FOR FORMING A PATTERNING COATING AND DEVICES INCORPORATING SAME NONO, EPHA4, EPHA6 LMNA 4297/4885THRB 4260/4885CA2 1412/4885
US-20230400764-A1 ORGANOMETALLIC COMPOUND COMPRISING A METAL COMBINED WITH AT LEAST ONE LIGAND CONTAINING FOUR OR MORE FLUORINE ATOMS, RESIST COMPOSITION COMPRISING THE SAME, AND METHOD OF FABRICATING SEMICONDUCTOR DEVICE USING THE SAME NR2C2, NR2F2, NR2E1 LMNA 4588/4885THRB 2006/4885CA2 761/4885
US-20070167481-A1 IMIDAZONAPHTHYRIDINES IFNG, IRF3, IFNAR1 LMNA 3209/4885THRB 3455/4885CA2 4467/4885
US-20180251468-A1 Ionic Liquid, Lubricating Agent, and Magnetic Recording Medium MUC1, JAK1, JAK3 LMNA 2468/4885THRB 3275/4885CA2 507/4885
US-20150353558-A1 Ionic Liquid, Lubricating Agent, and Magnetic Recording Medium MUC1, JAK1, JAK3 LMNA 2468/4885THRB 3275/4885CA2 507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.