Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | YWHAG | P61981 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419698 | 0.91 | NQO2 (0.47) | MAP4K4MKNK2CDC7ROCK2GSK3B | |
| SCHEMBL10594653 | 0.89 | MKNK2 (0.41) | MAP4K4MKNK2CDC7ROCK2GSK3B | |
| SCHEMBL17774803 | 0.76 | MITF (0.47) | MITFMAPTKDM4EMEN1THRB | |
| SCHEMBL1803658 | 0.73 | MAPT (0.53) | MAPTKDM4EMEN1THRBKMT2A | |
| SCHEMBL18669314 | 0.73 | PTGER4 (0.58) | MAPTKDM4EMEN1THRBKMT2A | |
| SCHEMBL2963768 | 0.73 | MAP2K2 (0.45) | MAP4K4MKNK2CDC7ROCK2GSK3B | |
| SCHEMBL5025115 | 0.73 | AKR1C3 (0.51) | MAPTKDM4EMEN1THRBKMT2A | |
| SCHEMBL29836246 | 0.72 | MKNK2 (0.42) | MAP4K4MKNK2CDC7ROCK2GSK3B | |
| SCHEMBL29835225 | 0.72 | KDM4E (0.48) | MKNK2MKNK1MAPTKDM4EMEN1 | |
| SCHEMBL2466385 | 0.72 | KDM4E (0.40) | MAP4K4MKNK2CDC7ROCK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308745-B1 | THICKENED MOULDING COMPOSITION | BASF Aktiengesellschaft (DE) | 1992-11-19 | — | — | EP | disclosed |