Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407225 | 1.00 | THRA (0.57) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL1606187 | 0.99 | THRA (0.56) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL28415892 | 0.97 | THRA (0.59) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL28422512 | 0.97 | THRA (0.59) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL28413250 | 0.97 | THRA (0.59) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL28418186 | 0.97 | THRA (0.59) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL28416770 | 0.97 | THRA (0.59) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL28413252 | 0.97 | THRA (0.59) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL28416774 | 0.97 | THRA (0.59) | THRATHRBPPARAPPARGLIPG | |
| SCHEMBL15174104 | 0.95 | THRA (0.57) | THRATHRBPPARAPPARGLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291521-B1 | SULFUR-CONTAINING COMPOSITIONS, LUBRICANT, FUEL AND FUNCTIONAL FLUID COMPOSITIONS | The Lubrizol Corporation (US) | 1992-12-30 | — | — | EP | disclosed |
| US-5141658-A | Extreme pressure lubricant; oxidation, wear, corrosion resistance | UNIVERSITY OF QUEENSLAND | 1992-08-25 | — | — | US | disclosed |
| EP-0448129-A2 | Sulfur-containing compositions, lubricant fuel and functional fluid compositions | The Lubrizol Corporation (US) | 1991-09-25 | — | — | EP | disclosed |
| EP-0291521-A1 | SULFUR-CONTAINING COMPOSITIONS, LUBRICANT, FUEL AND FUNCTIONAL FLUID COMPOSITIONS. | LUBRIZOL CORP (US) | 1988-11-23 | — | — | EP | disclosed |
| WO-1988003552-A2 | SULFUR-CONTAINING COMPOSITIONS, LUBRICANT, FUEL AND FUNCTIONAL FLUID COMPOSITIONS | THE LUBRIZOL CORPORATION (US) | 1988-05-19 | — | — | WO | disclosed |