SCHEMBL1606187

SCHEMBL1606187

CCCCCCCc1ccccc1OC(N)=S.NC(O)=S.[BaH2]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.56
THRB P10828 1/20 0.56
PPARA Q07869 3/20 0.48
PPARG P37231 2/20 0.48
LIPG Q9Y5X9 1/20 0.46
ALOX5 P09917 1/20 0.46
PTGS2 P35354 1/20 0.46
BID P55957 3/20 0.40
MCL1 Q07820 3/20 0.40
BCL2L1 Q07817 2/20 0.40
BAK1 Q16611 2/20 0.40
KAT8 Q9H7Z6 2/20 0.40
MEN1 O00255 1/20 0.40
NR1I2 O75469 1/20 0.40
LMNA P02545 1/20 0.40
CHRM2 P08172 1/20 0.40
CYP3A4 P08684 1/20 0.40
ADRA2A P08913 1/20 0.40
MAPT P10636 1/20 0.40
OPRK1 P41145 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4407225 0.99 THRA (0.57) THRATHRBPPARAPPARGLIPG
SCHEMBL9650772 0.99 THRA (0.57) THRATHRBPPARAPPARGLIPG
SCHEMBL28415892 0.96 THRA (0.59) THRATHRBPPARAPPARGLIPG
SCHEMBL28422512 0.96 THRA (0.59) THRATHRBPPARAPPARGLIPG
SCHEMBL28413250 0.96 THRA (0.59) THRATHRBPPARAPPARGLIPG
SCHEMBL28418186 0.96 THRA (0.59) THRATHRBPPARAPPARGLIPG
SCHEMBL28416770 0.96 THRA (0.59) THRATHRBPPARAPPARGLIPG
SCHEMBL28413252 0.96 THRA (0.59) THRATHRBPPARAPPARGLIPG
SCHEMBL28416774 0.96 THRA (0.59) THRATHRBPPARAPPARGLIPG
SCHEMBL15174104 0.94 THRA (0.57) THRATHRBPPARAPPARGLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 533 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4715023-A1 HEAT TRANSFER FLUID ExxonMobil Technology and Engineering Company (US) 2026-03-25 EP disclosed
EP-4715960-A1 METHOD FOR OPERATING A THERMAL MANAGEMENT ARRANGEMENT Dr. Ing. h.c. F. Porsche Aktiengesellschaft (DE) 2026-03-25 EP disclosed
US-20260081259-A1 METHOD FOR OPERATING A THERMAL MANAGEMENT ARRANGEMENT ExxonMobil Technology and Engineering Company (US) 2026-03-19 US disclosed
US-12358399-B2 Monitoring health of heat transfer fluids for electric systems ExxonMobil Technology and Engineering Company (US) 2025-07-15 US disclosed
CN-115605374-B Condition monitoring of heat transfer fluid for electrical systems 埃克森美孚技术与工程公司 2024-12-17 CN disclosed
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 US disclosed
US-20230166635-A1 MONITORING HEALTH OF HEAT TRANSFER FLUIDS FOR ELECTRIC SYSTEMS ExxonMobil Technology and Engineering Company (US) 2023-06-01 US disclosed
US-11629308-B2 Low viscosity gear oil compositions for electric and hybrid vehicles ExxonMobil Technology and Engineering Company (US) 2023-04-18 US disclosed
US-20230097718-A1 BIOBASED EXTREME PRESSURE ADDITIVE FOR LUBRICATING COMPOSITIONS AND ASSOCIATED METHODS INGEVITY SOUTH CAROLINA, LLC 2023-03-30 US disclosed
EP-4126588-A1 MONITORING HEALTH OF HEAT TRANSFER FLUIDS FOR ELECTRIC SYSTEMS ExxonMobil Technology and Engineering Company (US) 2023-02-08 EP disclosed
US-3980569-A LUBRICANTS THE LUBRIZOL CORPORATION (US) 1976-09-14 US disclosed
US-3979441-A DISPERSANTS, VISCOSITY MODIFIERS THE LUBRIZOL CORPORATION (US) 1976-09-07 US disclosed
US-3959159-A Nitrogen-containing mixed esters and lubricants THE LUBRIZOL CORPORATION (US) 1976-05-25 US disclosed
US-3957854-A FUEL ADDITIVES, LUBRICANTS THE LUBRIZOL CORPORATION (US) 1976-05-18 US disclosed
US-3957855-A FUEL ADDITIVES, LUBRICANTS THE LUBRIZOL CORPORATION (US) 1976-05-18 US disclosed
US-3956149-A CARBOXY-CONTAINING COPOLYMER THE LUBRIZOL CORPORATION (US) 1976-05-11 US disclosed
US-3953347-A EXTREME PRESSURE ADDITIVES FOR LUBRICANTS THE LUBRIZOL CORPORATION (US) 1976-04-27 US disclosed
US-3951830-A Basic metal salts of sulfur- and methylene-bridged polyphenol compositions, and epoxide-reacted derivatives thereof, and lubricants containing them THE LUBRIZOL CORPORATION (US) 1976-04-20 US disclosed
US-3948800-A Dispersant compositions THE LUBRIZOL CORPORATION (US) 1976-04-06 US disclosed
US-3932290-A Phosphorus-containing friction modifiers for functional fluids THE LUBRIZOL CORPORATION (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260081259-A1 METHOD FOR OPERATING A THERMAL MANAGEMENT ARRANGEMENT RAF1, PFKP, TP53RK THRA 1356/4885THRB 1310/4885PPARA 4507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.