Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 5/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 5/20 | 1.00 |
| ▸ | ADRA1B | P35368 | 5/20 | 1.00 |
| ▸ | DRD2 | P14416 | 8/20 | 0.73 |
| ▸ | DRD3 | P35462 | 8/20 | 0.73 |
| ▸ | DRD4 | P21917 | 6/20 | 0.73 |
| ▸ | HTR1A | P08908 | 4/20 | 0.73 |
| ▸ | DRD1 | P21728 | 1/20 | 0.70 |
| ▸ | HTR2A | P28223 | 1/20 | 0.70 |
| ▸ | HTR2C | P28335 | 1/20 | 0.70 |
| ▸ | HTR2B | P41595 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9652244 | 0.86 | ADRA1D (0.84) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL9653810 | 0.85 | DRD2 (0.93) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL9652267 | 0.84 | ADRA1D (0.81) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL14761722 | 0.84 | DRD2 (1.00) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL9652077 | 0.83 | ADRA1D (1.00) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL14761605 | 0.83 | DRD2 (0.98) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL10908587 | 0.83 | DRD2 (0.83) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL9652828 | 0.83 | DRD2 (0.81) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL19580052 | 0.83 | DRD2 (0.81) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL5507438 | 0.83 | DRD3 (1.00) | ADRA1DADRA1AADRA1BDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496692-A1 | 2-Methoxyphenylpiperazine derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1992-07-29 | — | — | EP | claimed |