Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.65 |
| ▸ | HPGDS | O60760 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | EED | O75530 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27254633 | 0.89 | DRD2 (0.60) | KMT2AMEN1LMNAHPGDSALDH1A1 | |
| SCHEMBL9037358 | 0.89 | DRD2 (0.63) | KMT2AMEN1LMNAGFERTSHR | |
| SCHEMBL612482 | 0.87 | AVPR1A (0.77) | KMT2AMEN1LMNAHPGDSALDH1A1 | |
| SCHEMBL7810111 | 0.85 | GFER (0.60) | KMT2AMEN1LMNAGFERHPGDS | |
| SCHEMBL7282092 | 0.84 | MEN1 (0.59) | KMT2AMEN1LMNAHPGDSALDH1A1 | |
| SCHEMBL27304741 | 0.83 | GFER (0.70) | GFERALDH1A1SMN1; SMN2HTTDRD2 | |
| SCHEMBL9036535 | 0.82 | MAPT (0.56) | KMT2AMEN1LMNAALDH1A1MAPT | |
| SCHEMBL14758395 | 0.81 | ALDH1A1 (0.81) | KMT2AMEN1LMNAHPGDSALDH1A1 | |
| SCHEMBL25404667 | 0.81 | MEN1 (0.62) | KMT2AMEN1LMNAHPGDSMAPT | |
| SCHEMBL13563662 | 0.81 | ALDH1A1 (0.64) | KMT2AMEN1LMNAGFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496692-A1 | 2-Methoxyphenylpiperazine derivatives | FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (FAES) (ES) | 1992-07-29 | — | — | EP | claimed |