SCHEMBL451221

SCHEMBL451221

CCCC(=O)c1cnc2c(OC)cccc2c1Nc1ccccc1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ATP4A P20648 1/20 1.00
ATP4B P51164 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29402089 1.00 ATP4A (1.00) ATP4AATP4B
Hydrochloric Acid SCHEMBL9652165 0.99 ATP4A (0.98) ATP4AATP4B
SCHEMBL9653867 0.94 ATP4A (0.89) ATP4AATP4B
SCHEMBL9652118 0.93 ATP4A (0.86) ATP4AATP4B
SCHEMBL9318845 0.92 ATP4A (0.85) ATP4AATP4B
SCHEMBL9650838 0.92 ATP4A (0.85) ATP4AATP4B
SCHEMBL9318536 0.91 ATP4A (0.84) ATP4AATP4B
SCHEMBL9319325 0.90 ATP4A (0.82) ATP4AATP4B
SCHEMBL9269573 0.90 ATP4A (0.82) ATP4AATP4B
SCHEMBL10498606 0.90 ATP4A (0.81) ATP4AATP4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0841904-B1 ORAL PHARMACEUTICAL COMPOSITIONS WITH DELAYED RELEASE OF REVERSIBLE PROTON PUMP INHIBITORS ALTANA PHARMA AG (DE) 2003-02-05 EP claimed
US-6132768-A FOR TREATING DISORDERS CAUSED BY HELICOBACTER BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 2000-10-17 US claimed
EP-0841904-A1 ORAL PHARMACEUTICAL COMPOSITIONS WITH DELAYED RELEASE OF REVERSIBLE PROTON PUMP INHIBITORS Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1998-05-20 EP claimed
WO-1997002021-A1 ORAL PHARMACEUTICAL COMPOSITIONS WITH DELAYED RELEASE OF REVERSIBLE PROTON PUMP INHIBITORS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1997-01-23 WO claimed
EP-0259174-B1 DERIVATIVES OF 4-AMINOQUINOLINE AND THEIR USE AS MEDICAMENTS SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1992-03-18 EP claimed
US-4806549-A INHIBITOR OF GASTRIC ACID SECRETION SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1989-02-21 US claimed
US-4806550-A 4-Amino-3-carbonyl substituted quinolines as inhibitors of gastric acid secretion SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) 1989-02-21 US claimed
EP-0259174-A1 Derivatives of 4-aminoquinoline and their use as medicaments SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1988-03-09 EP claimed
US-12616752-B2 Pharmaceutical compositions comprising meloxicam AXSOME THERAPEUTICS, INC. (US) 2026-05-05 US disclosed
US-12611413-B2 Pharmaceutical compositions comprising meloxicam AXSOME THERAPEUTICS, INC. (US) 2026-04-28 US disclosed
US-20260077048-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MELOXICAM AXSOME THERAPEUTICS INC (US) 2026-03-19 US disclosed
US-20260069603-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MELOXICAM AXSOME THERAPEUTICS INC (US) 2026-03-12 US disclosed
US-12551488-B2 Pharmaceutical compositions comprising meloxicam AXSOME THERAPEUTICS, INC. (US) 2026-02-17 US disclosed
US-12551489-B2 Pharmaceutical compositions comprising meloxicam AXSOME THERAPEUTICS, INC. (US) 2026-02-17 US disclosed
US-4806549-A INHIBITOR OF GASTRIC ACID SECRETION SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1989-02-21 US disclosed
US-4806549-A INHIBITOR OF GASTRIC ACID SECRETION SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1989-02-21 US disclosed
US-4806550-A 4-Amino-3-carbonyl substituted quinolines as inhibitors of gastric acid secretion SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) 1989-02-21 US disclosed
US-4806550-A 4-Amino-3-carbonyl substituted quinolines as inhibitors of gastric acid secretion SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) 1989-02-21 US disclosed
WO-1988001621-A1 4-AMINOQUINOLINE DERIVATIVES AND THEIR USE AS MEDICAMENTS SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1988-03-10 WO disclosed
EP-0259174-A1 Derivatives of 4-aminoquinoline and their use as medicaments SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1988-03-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12551488-B2 Pharmaceutical compositions comprising meloxicam SLC10A2, SLC10A1, CALCA ATP4A 567/4885ATP4B 1246/4885
US-12616752-B2 Pharmaceutical compositions comprising meloxicam SLC10A2, SLC10A1, CALCA ATP4A 611/4885ATP4B 941/4885
US-20260077048-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MELOXICAM SLC10A2, SLC10A1, CYP2C9 ATP4A 508/4885ATP4B 752/4885
US-20260069603-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING MELOXICAM SLC10A2, MC4R, CA4 ATP4A 248/4885ATP4B 480/4885
US-12551489-B2 Pharmaceutical compositions comprising meloxicam SLC10A2, SLC10A1, CYP2C9 ATP4A 426/4885ATP4B 796/4885
US-12611413-B2 Pharmaceutical compositions comprising meloxicam SLC10A2, SLC10A1, MC3R ATP4A 772/4885ATP4B 1994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.