Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | PTPRF | P10586 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250052 | 0.79 | KMT2A (0.59) | KMT2AMEN1PABPC1POLBRAB9A | |
| SCHEMBL4953680 | 0.78 | PTPRF (0.83) | KMT2AMEN1PTPRFPTPN2PTPN1 | |
| SCHEMBL28495692 | 0.77 | ALDH1A1 (0.62) | KMT2AMEN1PABPC1POLBRAB9A | |
| SCHEMBL1846278 | 0.77 | HDAC1 (0.51) | KMT2AMEN1RAB9ANPC1HDAC1 | |
| SCHEMBL30850667 | 0.76 | KMT2A (0.70) | KMT2AMEN1PABPC1POLBRAB9A | |
| SCHEMBL1851173 | 0.76 | KMT2A (0.70) | KMT2AMEN1PABPC1POLBRAB9A | |
| SCHEMBL18600198 | 0.74 | PTPRF (0.71) | KMT2AMEN1POLBPTPRFPTPN2 | |
| SCHEMBL12047913 | 0.74 | PTPRF (0.71) | KMT2AMEN1POLBPTPRFPTPN2 | |
| SCHEMBL3086465 | 0.74 | MEN1 (0.59) | KMT2AMEN1PABPC1POLBMAPT | |
| SCHEMBL22783774 | 0.74 | PTPRF (0.75) | KMT2AMEN1PTPRFPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153199-A | Pyridyl cyclopropane amide derivates for treating infections of plants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-06 | — | — | US | disclosed |
| EP-0434357-A2 | Fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-06-26 | — | — | EP | disclosed |