Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944345 | 0.78 | L3MBTL1 (0.60) | ALDH1A1MAPTMAPK1GAAL3MBTL1 | |
| SCHEMBL28487636 | 0.78 | HDAC1 (0.60) | ALDH1A1MAPTGAAKDM4EKMT2A | |
| SCHEMBL9650898 | 0.77 | KMT2A (0.63) | ALDH1A1MAPTGAAKDM4EKMT2A | |
| SCHEMBL29546539 | 0.75 | ALDH3A1 (0.66) | ALDH1A1MAPTMAPK1GAAL3MBTL1 | |
| SCHEMBL11745238 | 0.75 | ALDH3A1 (0.66) | ALDH1A1MAPTMAPK1GAAL3MBTL1 | |
| SCHEMBL15544374 | 0.74 | MEN1 (0.62) | ALDH1A1MAPTGAAL3MBTL1KDM4E | |
| SCHEMBL4250052 | 0.74 | KMT2A (0.59) | ALDH1A1MAPTKMT2AMEN1PABPC1 | |
| SCHEMBL6347219 | 0.73 | MEN1 (0.62) | ALDH1A1MAPTMAPK1L3MBTL1KMT2A | |
| SCHEMBL7512143 | 0.73 | ALDH3A1 (0.63) | ALDH1A1MAPTMAPK1GAAL3MBTL1 | |
| SCHEMBL27971590 | 0.73 | MAPT (0.71) | ALDH1A1MAPTMAPK1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868037-B | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2023-10-13 | — | — | CN | disclosed |
| CN-111868037-A | Fused cyclic urea derivatives as CRHR2 antagonists | 拉夸里亚创药株式会社 | 2020-10-30 | — | — | CN | disclosed |