Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.41 |
| ▸ | IL2 | P60568 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653141 | 0.94 | TLR7 (0.50) | TLR7TLR8IL2MRGPRX4CCR1 | |
| SCHEMBL9651062 | 0.93 | TLR7 (0.48) | TLR7TLR8IL2MRGPRX4CCR1 | |
| SCHEMBL9653077 | 0.90 | TLR7 (0.56) | TLR7TLR8IL2MRGPRX4FFAR1 | |
| SCHEMBL9654205 | 0.87 | TLR7 (0.46) | TLR7TLR8IL2MRGPRX4CCR1 | |
| SCHEMBL9652306 | 0.84 | TLR7 (0.43) | TLR7TLR8IL2MRGPRX4CCR1 | |
| SCHEMBL9653579 | 0.84 | LIPE (0.51) | TLR7TLR8GAAFFAR1 | |
| SCHEMBL9653604 | 0.83 | TLR7 (0.43) | TLR7TLR8IL2MRGPRX4CCR1 | |
| SCHEMBL9652559 | 0.80 | LIPE (0.51) | TLR7TLR8GAAFFAR1 | |
| SCHEMBL9654163 | 0.80 | GCGR (0.44) | MRGPRX4GAASCN8ASCN10AFFAR1 | |
| SCHEMBL10931887 | 0.79 | TLR7 (0.39) | TLR7TLR8GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263438-B1 | BENZOYLUREA COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-07-15 | — | — | EP | claimed |
| EP-0263438-A2 | Benzoylurea compounds, process for their production and pesticides containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1988-04-13 | — | — | EP | claimed |
| EP-0263438-B1 | BENZOYLUREA COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-4985449-A | N-benzoyl-N-pyridyloxy phenyl urea compounds and pesticide compositions containing them | ISHIHARA SANGYO KAISHA LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0263438-A2 | Benzoylurea compounds, process for their production and pesticides containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1988-04-13 | — | — | EP | disclosed |