Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653835 | 0.83 | POLB (0.31) | — | |
| SCHEMBL9651674 | 0.67 | GAA (0.31) | — | |
| SCHEMBL9422913 | 0.63 | — | — | |
| SCHEMBL9653524 | 0.60 | — | — | |
| SCHEMBL12603535 | 0.60 | TDP1 (0.41) | CA2ALDH1A1MAPT | |
| SCHEMBL9422808 | 0.58 | POLB (0.36) | — | |
| SCHEMBL8792481 | 0.58 | KDM4E (0.38) | ALDH1A1MAPT | |
| SCHEMBL17873714 | 0.56 | SMN1; SMN2 (0.39) | ALDH1A1MAPT | |
| SCHEMBL2175221 | 0.53 | L3MBTL1 (0.33) | ALDH1A1 | |
| SCHEMBL957578 | 0.53 | MEN1 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480745-A2 | Substituted dihydrothieno-thiophene-2-sulfonamides and dioxides thereof | MERCK & CO. INC. (US) | 1992-04-15 | — | — | EP | claimed |
| EP-0480745-A2 | Substituted dihydrothieno-thiophene-2-sulfonamides and dioxides thereof | MERCK & CO. INC. (US) | 1992-04-15 | — | — | EP | disclosed |