⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2419662 | 0.76 | — | — | |
| SCHEMBL4912202 | 0.73 | CHRM2 (0.40) | — | |
| SCHEMBL271887 | 0.71 | — | — | |
| SCHEMBL4911922 | 0.70 | CHRM1 (0.35) | — | |
| SCHEMBL667084 | 0.67 | — | — | |
| SCHEMBL2109441 | 0.67 | — | — | |
| SCHEMBL14023255 | 0.65 | CYP3A4 (0.41) | — | |
| SCHEMBL4915598 | 0.64 | CHRM3 (0.44) | — | |
| SCHEMBL6271467 | 0.64 | — | — | |
| SCHEMBL2199290 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023334-B | anti-GP 73 antibodies and immunoconjugates | 科雅博有限责任公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-116751298-A | anti-ROR 2 antibodies, antibody fragments and their immunoconjugates and uses thereof | 生物蛋白有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-116731174-A | anti-ROR 2 antibodies, antibody fragments and their immunoconjugates and uses thereof | 生物蛋白有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-116063515-A | anti-FCRH 5 antibodies | 基因泰克公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-114729041-A | High affinity nanobodies targeting B7H3(CD276) for the treatment of various solid tumors | 美国政府(由卫生和人类服务部的部长所代表) | 2022-07-08 | — | — | CN | disclosed |
| EP-3636636-B1 | PYRIDONE COMPOUND AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE | MITSUI CHEMICALS AGRO INC (JP) | 2022-07-06 | — | — | EP | disclosed |
| CN-114106185-A | anti-HER 2 antibodies and immunoconjugates | 基因泰克公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-113698485-A | anti-B7-H4 antibodies and immunoconjugates | 基因泰克公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-113698488-A | anti-B7-H4 antibodies and immunoconjugates | 基因泰克公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-107001479-B | anti-HER 2 antibodies and immunoconjugates | 基因泰克公司 | 2021-09-28 | — | — | CN | disclosed |
| US-20120283284-A1 | MELONINE BISINDOLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, PREPARATION METHOD AND USE THEREOF | KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCES (CN) | 2012-11-08 | — | — | US | disclosed |
| US-20110021517-A1 | ANTITUMOR COMBINATION COMPRISING A MORPHOLINYL ANTHRACYCLINE DERIVATIVE AND DEMETHYLATING AGENTS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2011-01-27 | — | — | US | disclosed |
| EP-2257310-A2 | ANTITUMOR COMBINATION COMPRISING A MORPHOLINYL ANTHRACYCLINE DERIVATIVE AND DEMETHYLATING AGENTS | Nerviano Medical Sciences S.r.l. (IT) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009106549-A2 | ANTITUMOR COMBINATION COMPRISING A MORPHOLINYL ANTHRACYCLINE DERIVATIVE AND DEMETHYLATING AGENTS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2009-09-03 | — | — | WO | disclosed |
| US-20080200475-A1 | 4-Piperazinothieno[2,3-D] Pyrimidine Compounds As Platelet Aggregation Inhibitors | PFIZER INC. | 2008-08-21 | — | — | US | disclosed |
| EP-1866317-A1 | 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | Pharmacia & Upjohn Company LLC (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006103555-A1 | 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-10-05 | — | — | WO | disclosed |
| EP-1605951-A1 | COMBINED THERAPY COMPRISING NEMORUBICIN AND A CYCLOOXYGENASE-2-INHIBITOR | Pharmacia Italia S.p.A. (IT) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004082689-A1 | COMBINED THERAPY COMPRISING NEMORUBICIN AND A CYCLOOXYGENASE-2-INHIBITOR | PHARMACIA ITALIA SPA (IT) | 2004-09-30 | — | — | WO | disclosed |
| US-4945038-A | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-07-31 | — | — | US | disclosed |