SCHEMBL9652500

SCHEMBL9652500

CN(C(=O)NC(=O)c1c(F)cccc1F)c1cc(F)c(-c2cccc(SC(F)(F)F)c2)cc1F

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
RORC P51449 4/20 0.32
IL2 P60568 3/20 0.32
RXFP1 Q9HBX9 2/20 0.32
PPIA P62937 1/20 0.31
TRPA1 O75762 3/20 0.31
KCNK2 O95069 1/20 0.31
CYP1A2 P05177 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
GPBAR1 Q8TDU6 1/20 0.30
RORA P35398 1/20 0.30
RORB Q92753 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4158996 0.84 TRPA1 (0.34) RORCRXFP1PPIATRPA1KCNK2
SCHEMBL4151343 0.82 ATM (0.35) PPIATRPA1CYP1A2
SCHEMBL4150976 0.80 MEN1 (0.39) RORCIL2
SCHEMBL4150857 0.80 RORC (0.36) RORCRXFP1TRPA1KCNK2CYP1A2
SCHEMBL9653668 0.79 RORC (0.39) RORCIL2
SCHEMBL4154004 0.78 TLR7 (0.42) RORCPPIA
SCHEMBL4150987 0.77 TRPA1 (0.36) PPIATRPA1CYP1A2
SCHEMBL4150579 0.76 TLR7 (0.39) PPIAKCNK2
SCHEMBL4151007 0.76 TRPA1 (0.33) RORCPPIATRPA1CYP1A2
SCHEMBL4149982 0.75 RORC (0.38) RORCALDH1A1RORARORB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108299352-A A kind of preparation method of furan dicarboxylic acid ester compounds 中国科学院宁波材料技术与工程研究所 2018-07-20 CN claimed
CN-108299353-A A kind of preparation method of 5- formic acid ester group furan compound 中国科学院宁波材料技术与工程研究所 2018-07-20 CN claimed
CN-103165446-B A kind ofly can be used for silica-based integrated HEMT device and preparation method thereof INSTITUTE OF SEMICONDUCTORS, CHINESE ACADEMY OF SCIENCES (CN) 2016-04-20 CN claimed
CN-103077892-B The method of integrated HEMT device on silicon INSTITUTE OF SEMICONDUCTORS, CHINESE ACADEMY OF SCIENCES (CN) 2015-08-19 CN claimed
CN-103165446-A HEMT (high electron mobility transistor) device available for silicon-based integration and method for preparing HEMT device INST SEMICONDUCTORS CAS 2013-06-19 CN claimed
CN-103077892-A Method for integrating high electron mobility transistor (HEMT) device on silicon INST SEMICONDUCTORS CAS 2013-05-01 CN claimed
EP-0263438-B1 BENZOYLUREA COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 1992-07-15 EP claimed
US-4861799-A INSSECTICIDES ISHIHARA SANGYO KAISHA LTD. (JP) 1989-08-29 US claimed
EP-0263438-A2 Benzoylurea compounds, process for their production and pesticides containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 1988-04-13 EP claimed
CN-108299352-B Preparation method of furan dicarboxylate compound 中国科学院宁波材料技术与工程研究所 2022-08-09 CN disclosed
CN-114773298-A Preparation method of 2, 5-disubstituted furan compound 中国科学院宁波材料技术与工程研究所 2022-07-22 CN disclosed
CN-114773299-A Preparation method of 2, 5-disubstituted furan compound 中国科学院宁波材料技术与工程研究所 2022-07-22 CN disclosed
CN-114751881-A Preparation method of furan dicarboxylic acid compound 中国科学院宁波材料技术与工程研究所 2022-07-15 CN disclosed
CN-108299380-B Preparation method of 2, 5-disubstituted thiophene compound 中国科学院宁波材料技术与工程研究所 2021-11-19 CN disclosed
US-4985449-A N-benzoyl-N-pyridyloxy phenyl urea compounds and pesticide compositions containing them ISHIHARA SANGYO KAISHA LTD. (JP) 1991-01-15 US disclosed
US-4861799-A INSSECTICIDES ISHIHARA SANGYO KAISHA LTD. (JP) 1989-08-29 US disclosed
US-4816496-A HEAT AND LIGHT RESISTANT ADHESIVES AND FILMS KABUSHIKI KAISHA TOSHIBA (JP) 1989-03-28 US disclosed
EP-0282634-A1 Photocurable composition KABUSHIKI KAISHA TOSHIBA (JP) 1988-09-21 EP disclosed
EP-0263438-A2 Benzoylurea compounds, process for their production and pesticides containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 1988-04-13 EP disclosed
EP-0172330-A1 Photocurable composition KABUSHIKI KAISHA TOSHIBA (JP) 1986-02-26 EP disclosed