Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CTSV | O60911 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.48 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.48 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.48 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653543 | 0.86 | C5AR1 (0.59) | C5AR1MEN1KMT2AKDM4ELTA4H | |
| SCHEMBL11548021 | 0.82 | NPC1 (0.68) | C5AR1MEN1KMT2AKDM4ESGMS2 | |
| SCHEMBL17372654 | 0.80 | NPC1 (0.60) | C5AR1MEN1KMT2AKDM4ECTSV | |
| SCHEMBL22502390 | 0.78 | C5AR1 (0.62) | C5AR1MEN1KMT2AKDM4ECTSV | |
| SCHEMBL11595438 | 0.77 | C5AR1 (0.69) | C5AR1KMT2APOLBMAPT | |
| SCHEMBL7322931 | 0.77 | NPC1 (0.63) | C5AR1MEN1KMT2AKDM4ECTSV | |
| SCHEMBL11264325 | 0.76 | C5AR1 (0.60) | C5AR1MEN1KMT2AKDM4EGAA | |
| SCHEMBL11276150 | 0.76 | C5AR1 (0.60) | C5AR1CTSVCTSL | |
| Hydrochloric Acid SCHEMBL11596870 | 0.76 | C5AR1 (0.67) | C5AR1KMT2APOLBMAPT | |
| SCHEMBL28776233 | 0.76 | FFAR4 (0.55) | C5AR1MEN1KMT2AKDM4ELTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243924-B1 | 2-OXO-1-(SUBSTITUTED PHOSPHOROUS)AZETIDINES | E.R. Squibb & Sons, Inc. (US) | 1992-12-23 | — | — | EP | disclosed |
| US-4723002-A | 1-(substituted phosphorous)-azetidinone antibacterials | E. R. SQUIBB & SONS, INC. | 1988-02-02 | — | — | US | disclosed |
| EP-0243924-A2 | 2-Oxo-1-(substituted phosphorous)azetidines | E.R. Squibb & Sons, Inc. (US) | 1987-11-04 | — | — | EP | disclosed |