Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6997144 | 0.82 | ELANE (0.53) | LMNAMEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL11458225 | 0.79 | TOP1 (0.50) | MEN1KMT2AMAPTKDM4EHSD17B10 | |
| Cyanate SCHEMBL8557741 | 0.78 | ELANE (0.45) | LMNAMEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL8557745 | 0.77 | ELANE (0.44) | LMNAMEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL1789230 | 0.76 | — | — | |
| SCHEMBL2010436 | 0.76 | LMNA (0.59) | LMNAMEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL9652679 | 0.75 | TSHR (0.60) | MAPTKDM4ESMN1; SMN2PKMGAA | |
| SCHEMBL414964 | 0.74 | LMNA (0.50) | LMNAMEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL16953510 | 0.74 | LMNA (0.50) | LMNAMEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL417129 | 0.72 | HSD17B10 (0.57) | LMNAMEN1KMT2AMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0189287-B1 | NOVEL B-LACTAM ANTIBIOTICS | NIPPON PHARMACEUTICAL DEVELOPMENT INSTITUTE COMPANY LIMITED (JP) | 1992-12-16 | — | — | EP | disclosed |
| US-4808711-A | EFFECTIVE AGAINST PSEUDOMONAS AERUGINOSA | SANKEI PHARMACEUTICAL CO., LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| EP-0189287-A2 | Novel B-lactam antibiotics | NIPPON PHARMACEUTICAL DEVELOPMENT INSTITUTE COMPANY LIMITED (JP) | 1986-07-30 | — | — | EP | disclosed |