Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | MRGPRX1 | Q96LB2 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9651520 | 0.86 | KMT2A (0.51) | MRGPRX1KMT2A | |
| SCHEMBL9499786 | 0.80 | KMT2A (0.46) | MRGPRX1KMT2A | |
| SCHEMBL221687 | 0.78 | METAP2 (0.53) | METAP2KDM4EKMT2A | |
| SCHEMBL31046886 | 0.78 | METAP2 (0.53) | METAP2KDM4EKMT2A | |
| SCHEMBL9321934 | 0.78 | MRGPRX1 (0.48) | METAP2MRGPRX1KDM4EKMT2A | |
| SCHEMBL9653888 | 0.76 | MRGPRX1 (0.43) | METAP2MRGPRX1KMT2A | |
| SCHEMBL9321851 | 0.72 | KMT2A (0.55) | KMT2A | |
| SCHEMBL12200769 | 0.71 | METAP2 (0.71) | METAP2KDM4EKMT2A | |
| SCHEMBL9882948 | 0.71 | MAPT (0.56) | METAP2KDM4EKMT2A | |
| SCHEMBL9651550 | 0.71 | MAPT (0.36) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130119-A | Sulfonamide or hydroxy fluorine substituted benzene for medical diagnosis | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |