Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 5/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653267 | 1.00 | GABRA1 (0.39) | GABRA1GABRG2GABRB3GABRB2AKR1C4 | |
| SCHEMBL9653677 | 0.83 | GABRA1 (0.55) | GABRA1GABRG2GABRB3GABRB2ALDH1A1 | |
| SCHEMBL9653670 | 0.83 | GABRA1 (0.55) | GABRA1GABRG2GABRB3GABRB2ALDH1A1 | |
| SCHEMBL9653689 | 0.83 | ALDH1A1 (0.47) | GABRA1GABRG2GABRB3GABRB2ALDH1A1 | |
| SCHEMBL9653681 | 0.83 | ALDH1A1 (0.47) | GABRA1GABRG2GABRB3GABRB2ALDH1A1 | |
| SCHEMBL9652081 | 0.77 | POLB (0.46) | ALDH1A1KDM4EHPGDDHODHEGFR | |
| SCHEMBL9652085 | 0.77 | POLB (0.46) | ALDH1A1KDM4EHPGDDHODHEGFR | |
| SCHEMBL9652675 | 0.76 | GABRA1 (0.44) | GABRA1GABRG2GABRB3GABRB2ALDH1A1 | |
| SCHEMBL9652671 | 0.76 | GABRA1 (0.44) | GABRA1GABRG2GABRB3GABRB2ALDH1A1 | |
| SCHEMBL32669585 | 0.74 | HSP90AA1 (0.35) | GABRA1GABRG2GABRB3GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213892-B1 | HERBICIDALLY ACTIVE ENOLS | ROHM AND HAAS COMPANY (US) | 1992-03-25 | — | — | EP | disclosed |
| US-4781750-A | Herbicidally active enols | ROHM AND HAAS COMPANY (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0213892-A2 | Herbicidally active enols | ROHM AND HAAS COMPANY (US) | 1987-03-11 | — | — | EP | disclosed |