Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653792 | 1.00 | GPR183 (0.60) | GPR183LMNAHPGDGAACYP1A2 | |
| SCHEMBL9654393 | 0.88 | HPGD (0.78) | GPR183LMNAHPGDGAACYP1A2 | |
| SCHEMBL9654396 | 0.88 | HPGD (0.78) | GPR183LMNAHPGDGAACYP1A2 | |
| SCHEMBL19385657 | 0.83 | GPR183 (0.67) | GPR183LMNAHPGDGAACYP1A2 | |
| SCHEMBL19385656 | 0.83 | GPR183 (0.67) | GPR183LMNAHPGDGAACYP1A2 | |
| SCHEMBL1615026 | 0.83 | GPR183 (0.63) | GPR183LMNAHPGDGAACYP1A2 | |
| SCHEMBL16599253 | 0.83 | GPR183 (0.63) | GPR183LMNAHPGDGAACYP1A2 | |
| SCHEMBL16599255 | 0.83 | GPR183 (0.63) | GPR183LMNAHPGDGAACYP1A2 | |
| SCHEMBL1615028 | 0.83 | GPR183 (0.63) | GPR183LMNAHPGDGAACYP1A2 | |
| SCHEMBL9654409 | 0.82 | RAB9A (0.75) | GPR183HPGDCYP1A2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192431-B1 | AGENT FOR CEREBRAL PROTECTION | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1992-12-16 | — | — | EP | disclosed |
| US-4962107-A | IMPROVED SIDE EFFECT REDUCTION | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1990-10-09 | — | — | US | disclosed |
| US-4824842-A | Cinnamoyl piperidines and thiomorpholine and cerebral protection compositions | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1989-04-25 | — | — | US | disclosed |