Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233807 | 0.79 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL16793322 | 0.78 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL9654037 | 0.78 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL11840322 | 0.77 | NOS2 (0.50) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL11794321 | 0.77 | PPARA (0.59) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL9440903 | 0.77 | ALDH1A1 (0.49) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL11213563 | 0.75 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL6082079 | 0.73 | ALDH1A1 (0.47) | SLC6A2SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL9423833 | 0.73 | ALDH1A1 (0.47) | KMT2AMEN1POLBSLC6A9LMNA | |
| SCHEMBL10225889 | 0.73 | ALDH1A1 (0.53) | KMT2AMEN1POLBSLC6A9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472118-A1 | Process for production of alpha,alpha-dialkoxycetones | BASF Aktiengesellschaft (DE) | 1992-02-26 | — | — | EP | disclosed |