Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.59 |
| ▸ | CCR5 | P51681 | 3/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9652487 | 0.92 | OPRM1 (0.55) | OPRM1CCR5BCHEACHECHRM2 | |
| SCHEMBL9654034 | 0.88 | OPRM1 (0.67) | OPRM1CCR5BCHEACHECHRM2 | |
| SCHEMBL9654272 | 0.87 | SIGMAR1 (0.57) | OPRM1CCR5BCHEACHECHRM2 | |
| SCHEMBL9651081 | 0.86 | OPRM1 (0.61) | OPRM1CCR5BCHEACHECHRM2 | |
| SCHEMBL9653715 | 0.86 | OPRM1 (0.61) | OPRM1CCR5BCHEACHECHRM2 | |
| SCHEMBL9653948 | 0.85 | OPRM1 (0.61) | OPRM1CCR5BCHEACHECHRM2 | |
| SCHEMBL9653759 | 0.84 | OPRM1 (0.65) | OPRM1CCR5BCHEACHECHRM2 | |
| SCHEMBL9653593 | 0.84 | OPRM1 (0.59) | OPRM1CCR5BCHEACHECHRM2 | |
| SCHEMBL9654111 | 0.83 | OPRM1 (0.56) | OPRM1CCR5BCHEACHECHRM2 | |
| SCHEMBL9651056 | 0.81 | OPRM1 (0.54) | OPRM1CCR5BCHEACHECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467325-A2 | Carbostyril derivatives | SYNTEX (U.S.A.) INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| US-5082847-A | Antiarrhythmia | SYNTEX (U.S.A.) INC. (US) | 1992-01-21 | — | — | US | disclosed |