Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 19/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8928418 | 0.90 | PTAFR (0.77) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL9661918 | 0.90 | PTAFR (0.73) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL9661997 | 0.87 | PTAFR (0.70) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| Pyrrole SCHEMBL9661972 | 0.87 | PTAFR (0.72) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL9662085 | 0.87 | PTAFR (0.72) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL9654262 | 0.86 | PTAFR (0.71) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL8928557 | 0.86 | PTAFR (0.73) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL9421185 | 0.86 | PTAFR (0.75) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL9661351 | 0.85 | PTAFR (0.74) | PTAFRCYP3A4ALOX15OPRK1PDE4D | |
| SCHEMBL9654335 | 0.85 | OPRK1 (0.76) | PTAFRCYP3A4ALOX15OPRK1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116971-A | Platelt-activating-factor antagonist | BOEHRINGER INGELHEIM KG (DE) | 1992-05-26 | — | — | US | disclosed |
| EP-0240899-A2 | 1,4-Diazepine | BOEHRINGER INGELHEIM KG (DE) | 1987-10-14 | — | — | EP | disclosed |